Use E-Utils to query dbSNP with a specific build
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9.9 years ago
legaultmarc ▴ 20

I am writing a script to get SNP positions from dbSNP by using NCBI E-Utils. When I use esearch and efetch to retrieve the positions, I can only access positions from the newest genome build. Since I want to use GRCh37, this causes problem. I was wondering if you knew of a way of asking for a specific assembly in E-Utils.

dbsnp ncbi eutils • 2.1k views
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9.9 years ago
David W 4.9k

dbSNP does not support searches for older assembly coordinates.

Depending on exactly what you are trying to do, you can probably use lift-over or remap to first convert your coordinates.

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