Purifying selection M7 and M8 models
1
1
Entering edit mode
8.7 years ago
RB ▴ 20

Dear All,

Can anyone suggest me how to utilize m7 and m8 models results to estimated purifying selection or relaxed constraints acting on your gene family.

Any other tutorial or methodology will also be helpful.

Thanks,
Reb

Purifyingselection codemlmodels • 2.4k views
ADD COMMENT
1
Entering edit mode
8.6 years ago
Martombo ★ 3.0k

You can use the program codeml from the package PAML, manual here

If you're new to programming you might find it easier to use the biopython implementation of PAML, it provides quite a user friendly interface to it and there are also examples you can follow.

ADD COMMENT

Login before adding your answer.

Traffic: 2554 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6