Question: Bowtie2 align not working
gravatar for K.Nijbroek
4.7 years ago by
K.Nijbroek100 wrote:

Hi All,

I've downloaded the latest version of Bowtie2 for Windows (, and added the executables directory to PATH. Whenever I try to run something via Bowtie2 I immediately get errors. If I just type 'bowtie2' I already get 'bowtie2-align-s.exe' has stopped working: (ERR): Description of arguments failed! Exiting now ... I've also tried commands which work perfectly with an older version of Bowtie2, same problem occurs.

Anyone knows what is going on? 

align windows bowtie2 • 2.5k views
ADD COMMENTlink modified 11 weeks ago by Biostar ♦♦ 20 • written 4.7 years ago by K.Nijbroek100

I get exactly the same. Did you ever figure this out?

ADD REPLYlink written 4.5 years ago by jonathanneve890
gravatar for dragana.dudic
2.5 years ago by
dragana.dudic0 wrote:

It's probably because of the chip architecture (my case). That means you are trying to install 64 bit (x86_64) software on 32 bit (i386-i686) machine. The last version that is made for 32 bit machines is Bowtie 2.1

ADD COMMENTlink modified 2.5 years ago • written 2.5 years ago by dragana.dudic0
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