Question: sequence alignment using a core alignment
1
gravatar for ronyc
3.5 years ago by
ronyc10
Israel
ronyc10 wrote:

Hi, 

I have an alignment between 4 proteins and I want to add each protein's sequence homolgs to it. Is there a tool where I can label my original alignment as a "core alignment" and not change it, and have the homolgs align according to this alignment?

Thanks!

alignment sequence • 932 views
ADD COMMENTlink modified 3.5 years ago by Dan Gaston6.9k • written 3.5 years ago by ronyc10
3
gravatar for Dan Gaston
3.5 years ago by
Dan Gaston6.9k
Canada
Dan Gaston6.9k wrote:

MAFFT lets you do this with the --add_sequence option: http://mafft.cbrc.jp/alignment/software/addsequences.html

Quite good alignment software, and I've used this option many times to add new sequences to existing alignments. 

ADD COMMENTlink written 3.5 years ago by Dan Gaston6.9k

Thanks so much! This is exactly what I was searching for, can't wait to try it out!

ADD REPLYlink written 3.5 years ago by ronyc10

You're welcome, glad to help. BTW it is good practice to upvote and accept an answer if it satisfies your question so that other people can more easily find the solution if they search for a similar problem. 

ADD REPLYlink written 3.5 years ago by Dan Gaston6.9k
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