chipseq and RNA-seq expression relation
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7.5 years ago
kanwarjag ★ 1.1k

I have basic understanding of Chipseq and RNA seq data and underlying biology, However, I am trying to understand is there a rule of thumb or standard relation if we perform chipseq and RNA seq (hor known TF). I mean RNA seq targets which are enriched in Chip seq will show upregulation or it can not be generalized. Any help in pointing to a previous discussion/ literature will be helpful.

Thanks

ChIP-Seq RNAseq • 1.8k views
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7.4 years ago
Ido Tamir 5.2k

This can not be generalized. One tool to check for associaton of TF-binding / RNA-Seq and target genes is http://cistrome.org/BETA/

Pubmed search for TF-activity you should be able to do yourself.

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