human functionaly related genes
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9.8 years ago
ravihansa82 ▴ 130

friends I need do find out list of functionally related genes.can any body suggests where I can find such data and I need to download them.

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9.8 years ago

I assume that you don't know about Gene Ontology. Check this link:

http://www.geneontology.org/

All the genes that have similar functions will share same Gene Ontology Term. For a gene there are three categories of GO terms: Molecular function, Biological process and Cellular compartments. The first two should be relevant to what you are looking for.

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thank you very much Ashuthosh...this is really help for me...ya I am not tht much of familiar with GO...thank for giving me this ideas...

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9.8 years ago
Whoknows ▴ 960

Hi

There is a lot of software which can help you if you would like to work on human or mice you can use:

DAVID Bioinformatics an online tool for gene ontology and functional clustering and also pathways.

Bingo a package for Cytoscape this tool could create nice network based your ontology information

But if you would like to find out about disease, gene ontology, disease or protein protein interaction data of your genes i highly recommend to use IPA ingenuity, it free for a week.

And take look at diseasome database maybe help you for disease related genes,

Hope it helps!!

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thank you very much pcsam....

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9.8 years ago

Depending on your specific application, you can also use tools/methods for gene prioritization/function prediction such as funl or GeneMANIA. The principle is that given a set of query genes related to a particular function, they rank the rest of the genome by some measure of functional similarity to the query genes. There are plenty of gene prioritization tools around with many listed here. Although many seem to be targeted at disease gene prioritization, depending on the data representation they use, they may also be suitable for measuring functional similarity.

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Jean...thanx lots for ur help......

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