Entering edit mode
9.8 years ago
michaelchen33
▴
20
SELEX method can detect strong binding sites after 10 to 15 cycles from the initial pool, but can the initial pool represent the whole human genome, so what SELEX detect is actually the strong binding sites in the human genome?
Doest it means that SELEX will missed most of the weak binding sites in the whole human genome?
Any suggestion or papers will help.
Thanks