Hello,

Does anyone know how the expected heterozygosity in lostian is calculated? I tried to find the equation but came up empty handed. The He reported in the program is on a scale from 0-1 so it is not simply a 2pq situation.

Expected heterozygosity in lositan

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8.4 years ago

emma.berdan
•
0

Hello,

Does anyone know how the expected heterozygosity in lostian is calculated? I tried to find the equation but came up empty handed. The He reported in the program is on a scale from 0-1 so it is not simply a 2pq situation.

0

Entering edit mode

8.4 years ago

tiagoantao
▴
690

In Lositan the Heterozygosity is `h_b`

rather than `h_t`

- i.e. it is the probability of choosing two alleles at random that are different, **one from each deme, rather than the prob of picking two alleles at random that are different irrespective of deme**. With two demes it can reach 1 when FST is 1. So the reason why it is so high is that you are probably looking at very inbred populations.

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