Question: Calculate mean mappability of genomic windows
1
gravatar for Irsan
5.4 years ago by
Irsan7.0k
Amsterdam
Irsan7.0k wrote:

I would like to calculate the mappability of 50 kb windows of Mus musculus assembly 9 (mm9). I downloaded the mappability with 100 bp reads from UCSC and created windows with bedtools makewindows -g myGenomeFile.txt -w 50000 > windows.bed

I cannot just calculate the mean mappability of all overlapping elements in the mappability track for each feature in the windows.bed file because the mappability windows from UCSC have different lenghts. I believe the UCSC binary bigWigAverageOverBed is specifically made for this job. However, I keep getting segmentation faults with this binary when I try it. I cannot find any solutions for this segmentation fault. What are my alternatives/options?

Many thanks in advance

genome • 1.7k views
ADD COMMENTlink modified 5.4 years ago • written 5.4 years ago by Irsan7.0k

Did you find a solution? I am getting this, too. Thanks.

ADD REPLYlink written 2.8 years ago by moxu440
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