Question: (Closed) Trying to Understand why and how NGS Reads follow Poisson Distribution
0
gravatar for vigprasud
4.9 years ago by
vigprasud60
United States
vigprasud60 wrote:

I am reading the basic concepts in NGS alignment and mapping and I understand the Poisson distribution characteristics of the short random reads generated by the sequencer machines are the key in designing these mapping algorithms either sequence wise or word matching methods.

 

Can someone explain and help me understand how the NGS reads follow poisson distribution?

 

 

ADD COMMENTlink written 4.9 years ago by vigprasud60
2

Check out this post: Why Does Rna-Seq Read Count Fit Poisson Distribution? 

ADD REPLYlink written 4.9 years ago by poisonAlien2.8k
1

You should try to phrase your question more precisely. The answer to your literal question is: "NGS reads do not follow a Poisson Distribution" The distribution defined for counts of events not for the reads itself.

ADD REPLYlink modified 4.9 years ago • written 4.9 years ago by Michael Dondrup46k
3
gravatar for Michael Dondrup
4.9 years ago by
Bergen, Norway
Michael Dondrup46k wrote:

Hello vigprasud!

Questions similar to yours can already be found at:

We have closed your question to allow us to keep similar content in the same thread.

If you disagree with this please tell us why in a reply below. We'll be happy to talk about it.

Cheers!

PS: Thanks pois(s)onAlien ;)
ADD COMMENTlink written 4.9 years ago by Michael Dondrup46k

Thank you guys. Shall follow the other thread. 

 

ADD REPLYlink written 4.9 years ago by vigprasud60

Haha.. I see what you did there :D

ADD REPLYlink written 4.9 years ago by poisonAlien2.8k
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