Question: Eqtl Analysis Of Snps And Cis- Or Trans-Related Genes
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gravatar for J.F.Jiang
9.6 years ago by
J.F.Jiang860
China
J.F.Jiang860 wrote:

Hello friends,

recently I want to have a look at relationship between some disease related SNPs and genes. It is mentioned in some papers that genes found in GWAS may be not the right one that really the casual gene or related gene. So the eQTL method should be applied to find the real ones.

Here I have collected some SNPs and those in LD with them. And I want to get all genes in "eQTL relationship" with them.

I have checked two references providing eQTL databases, but bad results have been obtained when LOD>=6 is applied.

Is there any other database I can use? Or could you offer me a better way to reach my goal?

Thank you very much!

gwas eqtl snp • 3.2k views
ADD COMMENTlink modified 9.6 years ago by Lars Juhl Jensen11k • written 9.6 years ago by J.F.Jiang860

I tried to fix up the text in the question - I hope I understood everything correctly. Could you please provide the two references for the databases that you have already checked?

ADD REPLYlink written 9.6 years ago by Lars Juhl Jensen11k

these are two commonly cited refs.

A genome-wide association study of global gene expression, Dixon et al,, Nature Genetics 39, 1202-1207 (2007). (mRNA_bySNP_browser_v1.0.1)

Population genomics of human gene expression, Stranger et al., Nature Genetics 39, 1217-1224 (2007).

ADD REPLYlink written 9.5 years ago by J.F.Jiang860
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