Question: Extract interactions between drug/drug-like compounds and genes from STITCH
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gravatar for chenyangls
4.6 years ago by
chenyangls10
United States
chenyangls10 wrote:

I want collect a set of compound-gene interactions for drug discovery purpose and turned to STITCH, since it contains interactions from multiple different sources like Drugbank and TTD. But it seems that STITCH also includes gene-gene interactions. Is there a way to systematically remove the gene-gene interactions and retain the information only for drugs and drug-like compounds?

gene • 926 views
ADD COMMENTlink modified 4.6 years ago by Sean Davis25k • written 4.6 years ago by chenyangls10
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gravatar for Sean Davis
4.6 years ago by
Sean Davis25k
National Institutes of Health, Bethesda, MD
Sean Davis25k wrote:

This is not a direct answer to your question, but it may suit your needs.  Take a look at the Drug-Gene Interaction database (DGIdb):

http://dgidb.genome.wustl.edu/

 

ADD COMMENTlink written 4.6 years ago by Sean Davis25k

Thanks! I just tried DGIdb and I think it only has data for human? I'll have to use a database containing several other species. 

ADD REPLYlink written 4.6 years ago by chenyangls10
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