Entering edit mode
9.6 years ago
Phil S.
▴
700
Hi,
I don't know whether it really fits in here but...
Does anyone of you have experience / a good review for modelling bacterial growth in blood?
I mean there is a ton out there for fed-batch reactors and stuff but is there something compareable for growing in blood?
Thanks,
Phil
Have you tried to find any information out before asking this question? There is a lot of information out there for bacterial growth models -- do any address growth in blood? What has your literature search shown you and how can you provide us with information to help address your question?
There are a lot of models, especially coming from white biotech. Ranging from the Monod Model up to models for small and larger bio-reactors. However, most of those only incorporate nutrient availability and such. Other models incorporate the effect of antibiotics. None (of which I found) gave me an Idea of how to model in real blood (not blood agar) though. Therefore I wanted to ask whether someone has an idea where to look for such a model. Sorry if the information given was a bit, say, sparse ;). As it seems to me right know I have to figure out some kind of combined model of those published myself.... On top of that most models only try to exactly model the so called growth and lag phase whereas I am particularly interested in the stable, pre-death phase of bacterial growth....
Thanks for your information -- perhaps not the most appropriate place to ask such an open ended question. I read this as a homework assignment question. I hope someone here will be able to help you -- I'm sorry I can't offer more help, but I've never worked with actual blood cultures (but yes on blood agar).
Actually it's not a homework... At the moment I got some samples on my hand which are drawn from blood cultures and I'm trying to test whether I can somehow estimate when the sample was drawn using growthmodels. Since there is non for blood (which I know of) I figured I'd ask here, even if it might not very well....