How much of human genome transcribe? How much of transcriptome are non-coding RNAs?
1
0
Entering edit mode
8.4 years ago
jack ▴ 960

Hi all,

I'm looking to understand, how many percent of human genome are transcribe? How much of transcriptome are protein coding an much are non-coding RNAs ?

next-gen genomics RNA-Seq • 8.7k views
ADD COMMENT
0
Entering edit mode

Exact number can not be given as this has cell type specificity. For example, there are much more non coding RNA and endogenous retroviral elements are expressed during development and in cancers which occupy much proportion of genome in comparison to that of normal differentiated cell types.

ADD REPLY
3
Entering edit mode
8.4 years ago

N.B. This is edited from the original, which was a post-closing comment. Due to that, some replies may not seem directly connected.

Have a look at this paper for some useful numbers.

In short, 5-10% of the human genome is transcribed and ~2% is protein coding.

ADD COMMENT
1
Entering edit mode

I disagree a bit here. I think that we all need to have a good sense of the sizes and magnitudes because they help us choose the right approaches, provide sanity checks and other estimates. It may not be computing related but it affects computing greatly.

ADD REPLY
2
Entering edit mode

Fair enough.

ADD REPLY
0
Entering edit mode

I am going to move the comment to an answer because the link in there does actually provide all the answers.

ADD REPLY
0
Entering edit mode

OK, I've reformatted it more as an answer and left a note mentioning why there are seeming non sequitor comments.

ADD REPLY
0
Entering edit mode

Istvan, you are completely right

ADD REPLY

Login before adding your answer.

Traffic: 2595 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6