Determination of cut-off in similarity score
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6.9 years ago
Nitin ▴ 150

Hello,

I computed semantic similarity score between gene ontology terms. Which ranges from 0 to 1. I want to choose cut-off in these 0 to 1 value. By which i can choose similar and dissimilar GO terms based on this cutt-off value. Can any body suggest some way how to determine significant cut-off

 

Thanks,

Sainitin

similarity cut-off • 2.0k views
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0.5 is halfway between them. If you want a justified level, you need a target or motivation. Maybe in your context the 95th percentile is more appropriate.
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