What is a non-diploid genome and its importance?

Question

[mangfu100]

Hi.

I have seen many times the word about non-diploid genome.

I already know the meaning of it.

In the point of view that human have pair of chromosomes, I can inference the meaning of diploid.

Anyway, what is a non-diploid genome and its importance?

While I was using DELLY detection software and read about it , I saw below FAQ and it arouse my curiosity.

Can DELLY be used on a non-diploid genome?

Yes and no. The SV site discovery works for any ploidy. However, the genotyping follows the classical hom. reference, het. and hom. alternative scheme.

As I mentioned above, I know the word 'diploid' meaning but I can link the word with above sentence.

Always the word about concept of genome is puzzled to me.

Thank you.

Answer 1

[Emily]

Certain organisms are haploid or have haploid stages to their life cycle. Some plants have very high ploidy, such as wheat which is hexaploid. The software expects to always find two possibilities at a given base position, so it will call haploid organisms as homozygous diploid and I have no idea it would handle multiploid calls with three or more alleles.