Mutate A Triplet From A Protein Sequence
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12.9 years ago
Flow ★ 1.6k

Given a protein sequence, is it there any experimental method that allows to detect a given triplet and change or mutate it to another one?

sequence mutation • 2.3k views
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If by "experimental method" you mean "in the laboratory", then this is not a bioinformatics question and should be closed. And if you're looking for publications, you should learn how to search literature effectively.

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In what organism?

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Triplet is a confusing word. Are you asking about a codon triplet, or, as I interpret your questions, do you want to know about detecting a 3-amino acid sequence within the larger polypeptide? Both can be detected and can be mutated.

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yes Larry, exactly that. I would like to get the most representative references or publications about that, thanks

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I tried it but found nothing; which keywords would you use? codon + triplet + mutate ?

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What you are looking for called "Site-directed mutagenesis".

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12.9 years ago
Omid ▴ 580

I think you can do it by site directed mutagenesis

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