I have some INDELS which I have found out using the VarScan2. However I did not use the vcf output and also the am only caring about somatic indels. So I filter the indel output of VarScan2 and just retain the somatic indels in a .txt file in the below format.
chr1 976506 A -GCGGGGGC chr1 1141864 C +G chr1 1417649 T -C chr1 1454046 T -AC chr1 2117710 A -C chr1 2494360 C -T chr1 2985791 A +G
I now want to annotate this using VEP. I have already annotated with Annovar and it works fine but it does not work with the VEP tool at ENSEMBL website as the format is not compatible. I also created a script to convert .txt file to vcf4 format which worked well with annovar for the same .txt indels which I converted to vcf4 format with my script. But this vcf files are not being recognized by ENSEMBL website. So my only way is to make this format somewhere compatible with VEP online. Can anyone suggest me a script or way how to do it? Or does anyone have any other script to tranform .txt to VCF4 that is compatible with ENSEMBL VEP tool in their webpage? I would appreciate some leads in this front.