tool for enrichment analysis of miRNA

Question

[seta]

Dear all,

I'm looking for a tool for doing miRNA enrichment analysis. we usually do gene enrichment analysis using DAVID, but it doesn't support miRNA. Any suggestion would be highly appreciated.

Answer 1

[Zhilong Jia]

How To Do Pathway Analysis For Mirna Regulation

http://www.ncbi.nlm.nih.gov/pubmed/23007502

[seta]

Thanks for your reply, however as far as I check the first tool is suitable for pathway analysis, and later is for miRNA target. My focus is on performing just enrichment analysis on miRNA, not their targets. I need more suggestions

[Zhilong Jia]

To do the enrichment analysis, firstly, we need an annotation database, which contains items, maybe like GO or KEGG pathway. For each item, it contains a list of miRNA. So what's the items you want for this kind of enrichment analysi of miRNA? I believe that's the key.

[seta]

Yes, that's right. GO, KEGG and everything that help to this analysis. Also, the connection between miRNAs and disease is important for me. I know that because of deficiency in miRNA filed, this kind of tool maybe not much available as compared with gene enrichment analysis tool, so many people use their target to do this analysis. Hope there is such tool to do analysis directly on miRNA.

[hasan]

You can use "miSEA:microRNA set enrichment analysis"

http://www.baskent.edu.tr/~hogul/misea

Answer 2

[hasan]

http://www.baskent.edu.tr/~hogul/misea

Answer 3

[jiang.changaging]

http://www.mirbase.org/