Question

Finding Human/Yeast Orthologs Using Embl?

4

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12.6 years ago

Blizclaw ▴ 40

Hi, I am new at using EMBL and I need to find orthologues between the genes of chromosome 7 of Saccharomyces cerevisiae and humans. I have a feeling it can be done with Ensembl, but I am not quite sure how to go about doing it. Any tips?

Thanks!

orthologues • 9.2k views

ADD COMMENT • link updated 12.6 years ago by Rama ▴ 40 • written 12.6 years ago by Blizclaw ▴ 40

Ram · Answer 1 · 2011-09-18

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12.6 years ago

Casey Bergman 18k

Try doing this using BioMart by adapting the following protocol: http://www.ensembl.info/blog/2009/01/21/how-to-get-all-the-orthologous-genes-between-two-species/

ADD COMMENT • link updated 4.6 years ago by Ram 43k • written 12.6 years ago by Casey Bergman 18k

score 1 · Answer 2 · 2011-09-18

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12.6 years ago

Khader Shameer 18k

You may also check: Ensembl Compara for finding human-yeast orthologs.

ADD COMMENT • link 12.6 years ago by Khader Shameer 18k

score 1 · Answer 3 · 2011-09-19

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12.6 years ago

Rama ▴ 40

Hi,

You can use YeatMine at Saccharomyces Genome Database to find homologs.You have to build a query to find the homologs. Send an email to sgd-helpdesk@lists.stanford.edu if you encounter problems. http://yeastmine.yeastgenome.org/yeastmine/begin.do

R

ADD COMMENT • link 12.6 years ago by Rama ▴ 40