Nucleotide sequence of an Enzyme
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6.9 years ago

Hi,

I want to download nucleotide sequence of all hydrolases and Isomerases enzyme found in humans. Please suggest me how to download them all at a time.

enzyme protein nucleotide sequence download • 3.1k views
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http://www.uniprot.org/uniprot/?query=hydrolases&sort=score

in this case you have all hydrolases on the left you can apply the selection humans (353 sequences) and download it.

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Thanks for reply, but this will give me amino acid sequence of those 353 sequences and I am asking for nucleic acid sequence.

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6.9 years ago
a.polo88 ▴ 110

hi, on uniprotkb you can search for hydrolases and isomerases sequences then you can selected the species in this case human and select all and click on download.

example :

http://www.uniprot.org/uniprot/?query=hydrolases&fil=organism%3A%22Homo+sapiens+%28Human%29+[9606]%22&sort=score

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your method will give me amino acid sequence only but not nucleotide sequence of those enzymes and I am looking for nucleotide sequence of enzymes.

thanks anyway.

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6.9 years ago

search GO for hydrolase: http://amigo.geneontology.org/amigo/term/GO:0016787

download the genes associated to this term: Gene Names From Go Accessions Numbers

then get the sequences: How To Download Gene Sequences From Ncbi Gene

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it's is true him ask about nucleotide sequences i have seen bad but in this case is not to much simple to use ensembl?

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6.9 years ago

You can try the following Ensembl biomart query.

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