Please take a look at HeatmapGenerator: http://www.scfbm.org/content/9/1/30
HeatmapGenerator is a graphical user interface software program written in C++, R, and OpenGL to create customized gene expression heatmaps from RNA-seq and microarray data in medical research with simple clicks of a button to help you (the researcher) save time and money.
To use HeatmapGenerator, please download either the Apple Mac OSX or Microsoft Windows binaries from here: https://sourceforge.net/projects/heatmapgenerator/
You can easily follow along with me on my YouTube video and see HeatmapGenerator in action:
For interested software developers, HeatmapGenerator source code is available for viewing at: https://github.com/Bohdan-Khomtchouk/HeatmapGenerator
HeatmapGenerator is free software (released under the GNU General Public License) and you are welcome (and encouraged) to contribute to it. Please feel free to get in touch with me at firstname.lastname@example.org, Github, or here on Biostars.