Forum: What Are The Most Influential Bioinformatics/Computational Biology Papers Of 2014?
7
gravatar for dago
3.5 years ago by
dago2.5k
Germany
dago2.5k wrote:

I really liked this discussion:

What Are The Most Influential Bioinformatics/Computational Biology Papers Of 2011?

Therefore, I think it would be nice to have it also for 2014.

This is a really good way of having an overview about what happened in the last year.

papers forum • 1.7k views
ADD COMMENTlink modified 3.5 years ago by Istvan Albert ♦♦ 77k • written 3.5 years ago by dago2.5k
1
gravatar for Istvan Albert
3.5 years ago by
Istvan Albert ♦♦ 77k
University Park, USA
Istvan Albert ♦♦ 77k wrote:

IMHO having the MinION produce useful data may turn out to be the most influential development - though there is no singular paper to point to.

https://nanoporetech.com/technology/the-minion-device-a-miniaturised-sensing-system/the-minion-device-a-miniaturised-sensing-system

ADD COMMENTlink modified 3.5 years ago • written 3.5 years ago by Istvan Albert ♦♦ 77k
1

Just to add some new information to the MinION topic:

Improved data analysis for the MinION nanopore sequencer

 

ADD REPLYlink modified 3.3 years ago • written 3.3 years ago by dago2.5k

thanks for posting it - I am very interested in the technology and the latest developments

ADD REPLYlink written 3.3 years ago by Istvan Albert ♦♦ 77k

This is awesome to hear. I'm still wondering how these things deal with single stranded RNA virus genomes. The problem there is that there's usually a ton of structure in the 5'/3' UTRs. With 'normal' NGS these regions can have poor coverage but I wonder how well they would fit through a pore. It would be nice to not have to do RACE to get a full genome sequence.

Or for that matter how well can you deal with cDNA generated from viral genomes?

I really wish they'd start selling them already.

ADD REPLYlink modified 3.3 years ago • written 3.3 years ago by pld4.7k

Sorry my ignorance, are you refering tho this: https://www.biostars.org/p/86819/?

ADD REPLYlink written 3.5 years ago by dago2.5k
3

it is actually this https://nanoporetech.com/technology/the-minion-device-a-miniaturised-sensing-system/the-minion-device-a-miniaturised-sensing-system

turns out the word MinION is not all that searchable on the account of the Despicable Me movies

ADD REPLYlink written 3.5 years ago by Istvan Albert ♦♦ 77k

Google should really add case sensitive search.

Alternatively, Oxford can ship the device in a special Blue-and-Yellow Googly Eyed edition :D

ADD REPLYlink modified 3.5 years ago • written 3.5 years ago by Ram15k
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