minor introns database
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6.8 years ago
Martombo ★ 2.9k

Hello,

I'm interested in studying minor introns in both humans and mice. I'm therefore looking for a database collecting this kind of introns.

I know U12DB, but it is based on an analysis that was performed in 2006 (almost ten years ago!) and many of those introns don't really match with an intron of the most recent assembly (especially for the mouse genome). So I'm not really eager to use it. Do you know any other, more recent, such database?

database minor introns • 1.3k views
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Entering edit mode
6.8 years ago
Martombo ★ 2.9k

at the end, U12DB was not too bad. I was mislead by the fact that the developer of the database told me it was based on mm9, while it was actually mm6. 90% of the mm6 introns could be ported to mm10 and matched with an intron. so in conclusion it can still be used, even though it's probably quite far from being complete (550 minor introns in mouse).

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12 months ago
Martombo ★ 2.9k

Hello me from 5 years ago. A new genome-wide search of minor introns has been performed and it led to the discovery of ~150 more minor introns (doi.org/10.1186/s12864-019-6046-x).

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