I have been working with TCGA cancer data to examine expression (RNAseqV2) and methylation (Illumina 450k) data. I want to look at sequencing data, but I'm a bit lost to what sort of information is available through TCGA. I want to examine whether there are nonsense mutations between positions 2000-2500 across all cancer types available in TCGA. What sort of resources/workflow should I expect?
Appreciate it! Thank you