Question: Is there a database of disease prevalence by indication ( and any other bonus data) ?
gravatar for Wayne
4.7 years ago by
United States
Wayne1.0k wrote:

Hey guys, 

My lab is looking to apply a new computational technique to some diseases with high unmet need. 

I've found however, that trying to establish what diseases have high unmet need on a systematic level is very difficult.

No matter where I look I cant seem to find a database that has.

Disease \t Prevalence \t Mortality \t (any bonus data)


Does anyone have any ideas for how to find this. Id like to end up with a way to rank the diseases so that either ones with large patient populations or ones with small patient populations but terrible quality of life or high mortality can be identified. 

Any ideas would be super helpful, as I could then cross this list with OMIM and get genes for each....and start the road down to some good science of course.



ADD COMMENTlink modified 4.7 years ago by cdsouthan1.8k • written 4.7 years ago by Wayne1.0k

Have you considered the CDC's "wonder" database? It's more oriented toward epidemiology, but at least you can get some useful mortality information from it.

ADD REPLYlink written 4.7 years ago by Devon Ryan92k

I did, its very useful for infectious disease and select few others but not much on other things..... it is the kind of thing I'm looking for but just need something that is as comprehensive as ICD10 codes or OMIM

ADD REPLYlink written 4.7 years ago by Wayne1.0k

My only other guess would be to contact an insurance company, since they would have information on prevalence (don't know if they track mortality information).

ADD REPLYlink written 4.7 years ago by Devon Ryan92k

Out of curiosity, how do you plan to establish quality of life impacts with disease? You could identify symptoms associated with those diseases but how do you account for severity, duration, co-occurrence and frequency?

ADD REPLYlink written 4.7 years ago by pld4.8k

It certainly isn't easy you're totally right, but the idea was to use metrics like "DALYs" (Disability adjusted life years). This will definitely be the hardest bit.

ADD REPLYlink written 4.7 years ago by Wayne1.0k

Did you ever find anything?

ADD REPLYlink written 2.8 years ago by gregorymcinnes10
gravatar for Pierre Lindenbaum
4.7 years ago by
France/Nantes/Institut du Thorax - INSERM UMR1087
Pierre Lindenbaum123k wrote:

In france/French CEPIDC  (no data available for download AFAIK ) :

something under WHO "Global Health Observatory (GHO) data" ?

ADD COMMENTlink written 4.7 years ago by Pierre Lindenbaum123k

Thanks for the answer, 

Maybe I am missing something but on several attempts I wasn't able to find what I needed form WHO as they don't really have the data at the granularity I need. They have prevalence of larger scale things ( like COPD, Asthma, Tobacco Use, etc) or morbities  by country but I really need to get deeper down into an OMIM or ICD10 code view of diseases. 

ADD REPLYlink written 4.7 years ago by Wayne1.0k
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