Protein structure distorted after energy minimization using GROMACS

Question

[BI]

I have generated one protein structure from phyre2 using intensive mode. I tried to energy minimize it using GROMACS but unfortunately the resulting structure is completely distorted. Is there any way I can fix this problem? I appreciate your help on this.

Answer 1

[venu]

The information you have provided is very insufficient for any one to answer this or fix this problem. Possibly this might be a consequence of high temperature. Do the energy minimization with low temperature than the initial, then compare the result.