I have variations from different humans (next gen sequence). Some of these variations are known SNPs in the dbSNP database. I want to get more information on those SNPs. My options are UCSC mysql database, download tables from UCSC, query dbSNP using e-utils, dowload from dbSNP ftp. The number of SNPs that I will check is in the hundreds. Which way do you think is best? I can query dbSNP with python but I am not sure how to parse the output or if this is the best way to achieve my goal. Any input is appreciated. Thanks
Varietas is interesting. Do they have a download options to get the raw files ?
Unfortunately it seems that there is no download section. But you can download the result of your query as tsv file.
The weblink is dead, please update.
Try Annovar http://www.openbioinformatics.org/annovar/ is quite a powerful Variant annotation tool.