Question: Case and control in microarray/RNA-seq analysis
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gravatar for mahdijalili
5.7 years ago by
mahdijalili20
Iran, Islamic Republic Of
mahdijalili20 wrote:

Hi, Can I use the case samples from a study and the control samples from another study in microarray/RNA-seq analysis? (specially for cross-study analysis with Bioconductor RankProd R package)

Thanks.

rna-seq microarray • 1.4k views
ADD COMMENTlink modified 5.7 years ago by Manvendra Singh2.1k • written 5.7 years ago by mahdijalili20
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gravatar for Manvendra Singh
5.7 years ago by
Manvendra Singh2.1k
Berlin, Germany
Manvendra Singh2.1k wrote:

If they are stable cell lines then I believe Yes, you can use it but if they are patient materials then I doubt.

All you need is robust normalization andĀ RankProd would remove False discoveries., after that cluster them to see if they look different

ADD COMMENTlink written 5.7 years ago by Manvendra Singh2.1k
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