Case and control in microarray/RNA-seq analysis
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9.6 years ago
mahdijalili ▴ 20

Hi, Can I use the case samples from a study and the control samples from another study in microarray/RNA-seq analysis? (specially for cross-study analysis with Bioconductor RankProd R package)

Thanks.

microarray RNA-seq • 1.8k views
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9.6 years ago
Manvendra Singh ★ 2.2k

If they are stable cell lines then I believe Yes, you can use it but if they are patient materials then I doubt.

All you need is robust normalization and RankProd would remove False discoveries., after that cluster them to see if they look different

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