Question: is there any suitable drugs pathway analysis online tools?
0
gravatar for Mo
4.5 years ago by
Mo890
/
Mo890 wrote:

In my search, I could not find any easy to use and suitable online web. I have names of several drugs (only their names) I would like to know whether there is any tools that I can use for pathway analysis of them ? if so, which types of information can I obtain by using it? 

 

pathway analysis drugs • 1.4k views
ADD COMMENTlink modified 2.8 years ago by Diwan560 • written 4.5 years ago by Mo890

You said you have several drugs names. What is the purpose of finding pathway analysis in them??

ADD REPLYlink written 3.4 years ago by Naresh60
2
gravatar for muratiskar
2.8 years ago by
muratiskar20
muratiskar20 wrote:

You can have a look at Chemical Annotation Retrieval Toolkit available from:

http://cart.embl.de/

It matches an input list of chemical names to Pubchem IDs.

Later, bioactivity annotations (including pathways, protein targets) can be easily retrieved from CART.

Also, it is possible to perform chemical/drug annotation enrichment using the same toolkit.

ADD COMMENTlink written 2.8 years ago by muratiskar20

Thanks for pointing to this resource. Looks interesting!

ADD REPLYlink written 2.8 years ago by Diwan560
1
gravatar for Denise - Open Targets
3.4 years ago by
UK, Hinxton, EMBL-EBI
Denise - Open Targets5.0k wrote:

Try searching for the drug name in the Reactome database e.g. paracetamol. There is ChEMBL and ChEBI too but not sure if they provide pathway information but worth investigating them further.

ADD COMMENTlink written 3.4 years ago by Denise - Open Targets5.0k
1
gravatar for natasha.sernova
3.4 years ago by
natasha.sernova3.6k
natasha.sernova3.6k wrote:

It turned out, KEGG has a special site:

http://www.genome.jp/kegg/drug/

It provides pathways at the bottom of the corresponding pages, like this one:

http://www.kegg.jp/pathway/hsa05010

Also, try to look at close biostar-posts.

Is There A Free Alternative To Ingenuity Pathway Analysis?

Biological Pathways And Drug Designing

ADD COMMENTlink modified 3.4 years ago • written 3.4 years ago by natasha.sernova3.6k
1
gravatar for Diwan
2.8 years ago by
Diwan560
United States
Diwan560 wrote:

You can search for your drug in PubChem too. They have a section called "Biomolecular interaction and pathways".

For example, search for celecoxib: https://pubchem.ncbi.nlm.nih.gov/compound/2662#section=Biosystems-and-Pathways

(or) check NCBI Biosystems directly too. https://www.ncbi.nlm.nih.gov/biosystems

ADD COMMENTlink written 2.8 years ago by Diwan560
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