Same rs identifier for multiple SNPs

Question

[AcoBetalow]

Hi everybody,

I found many threads concerning multiple rs identifiers for single SNP, but my problem is quite the opposite.

Using BioMart I try to do whole genome analysis for deleterious SNPs in different organisms. To my surprise I constantly get many locations and many different genes for same rs identifier. Could this be because of duplications, orthologues, paralogues...? Here is an example for "rs108080416" in Mus musculus on Y chromosome:

Variation.Name     Chromosome.position.start..bp.     Chromosome.position.end..bp.     Strand     Ensembl.Gene.ID
rs108080416        70464491                           70464491                         -1         ENSMUSG00000094616
rs108080416        71714552                           71714552                         -1         ENSMUSG00000100535
rs108080416        72224547                           72224547                         1          ENSMUSG00000096902
rs108080416        73691822                           73691822                         -1         ENSMUSG00000099782
rs108080416        74493272                           74493272                         -1         ENSMUSG00000101528
rs108080416        75218384                           75218384                         -1         ENSMUSG00000101146
rs108080416        75737883                           75737883                         -1         ENSMUSG00000100902
rs108080416        77715389                           77715389                         -1         ENSMUSG00000094647
rs108080416        65400236                           65400236                         -1         ENSMUSG00000093993
rs108080416        68272307                           68272307                         1          ENSMUSG00000096016
rs108080416        68810257                           68810257                         1          ENSMUSG00000100032
rs108080416        64495766                           64495766                         -1         ENSMUSG00000101766
rs108080416        57209714                           57209714                         -1         ENSMUSG00000101155
rs108080416        57728261                           57728261                         -1         ENSMUSG00000101399
rs108080416        61669220                           61669220                         -1         ENSMUSG00000100726
rs108080416        62213469                           62213469                         -1         ENSMUSG00000094821
rs108080416        63250982                           63250982                         -1         ENSMUSG00000100856
rs108080416        52802573                           52802573                         -1         ENSMUSG00000095606
rs108080416        55236225                           55236225                         -1         ENSMUSG00000094570
rs108080416        55754273                           55754273                         -1         ENSMUSG00000095135
rs108080416        22838749                           22838749                         1          ENSMUSG00000103919
rs108080416        26754269                           26754269                         1          ENSMUSG00000100055
rs108080416        27499390                           27499390                         1          ENSMUSG00000099541
rs108080416        49593757                           49593757                         -1         ENSMUSG00000095979
rs108080416        8280450                            8280450                         -1          ENSMUSG00000101928

Thank you in advance for all your help.

Best regards, Aco

Answer 1

[Pierre Lindenbaum]

see Dbsnp Records That Map To Multiple Genome Locations ; Multiple Entries With The Same Rs Number In Dbsnp131 ; Snp Maps To 2 Chromosomes

[AcoBetalow]

Thank you Pierre, I get it now =)