I am a beginner level bioinformatician planning to work on "Analysing and interpreting the 450k methylation data for 70 odd samples from TCGA for a particular cancer". I intend to find DMRs when comparing tumor samples and normal samples. Later on I would like to co-relate the gene expression data with the methylation data.
Do you think this is a good research topic? Can you provide insight on what more can I do considering this is a six-months project? I will really appreciate your responses as I don't really have a 450k-savvy specialist/mentor anywhere around me.