Question: gene expression profiling
0
gravatar for bioinfo
3.9 years ago by
bioinfo50
research
bioinfo50 wrote:

After getting the hub genes or bio marker genes through re analysis of the available GEO data sets by bioinformatics tools, what all further analysis are needed to verify the current results???

gene • 701 views
ADD COMMENTlink modified 3.9 years ago by Devon Ryan88k • written 3.9 years ago by bioinfo50
0
gravatar for Devon Ryan
3.9 years ago by
Devon Ryan88k
Freiburg, Germany
Devon Ryan88k wrote:

Your post can be rephrased, "I've made a model, how do I test its accuracy?"

The general options for testing the accuracy of a model are:

  1. Use datasets not used for model creation to see how predictive/accurate it is.
  2. Do a bench experiment where you perturb something important in the model and check if the actual and theoretical results match.

Of course, you might want to check the literature too to ensure that your model is biologically reasonable.

ADD COMMENTlink written 3.9 years ago by Devon Ryan88k

Hi... I am finding it difficult to understand yr reply.. Can yu please explain me in an easier way

ADD REPLYlink written 3.9 years ago by bioinfo50

What part don't you understand?

ADD REPLYlink written 3.9 years ago by Devon Ryan88k

Regarding model !!! As i havent made any model... i jus used the existing bioinformatics tools to analyse the GEO datasets and i got the hub genes!!!!

ADD REPLYlink written 3.9 years ago by bioinfo50

You've constructed a network. That network is a model.

ADD REPLYlink written 3.9 years ago by Devon Ryan88k

Thanks... Can you please give yr email id... i am having so many doubts in gene expression profiling.

ADD REPLYlink written 3.9 years ago by bioinfo50

Just post your questions to the site.

ADD REPLYlink modified 3.9 years ago • written 3.9 years ago by Devon Ryan88k

okie... thanks!!!

ADD REPLYlink written 3.9 years ago by bioinfo50
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1699 users visited in the last hour