Question: Not Annotated Genome
0
gravatar for mariano.avino
3.9 years ago by
European Union
mariano.avino0 wrote:

Hi there,

Is there any 'model' organism (plant, animal, bacterial) out there you would say it has not been annotated or, at least, bad annotated?

Thank you very much in advance.

Mariano

 

 

genome • 899 views
ADD COMMENTlink modified 3.8 years ago by h.mon24k • written 3.9 years ago by mariano.avino0

I guess most of the reference organisms with available genomes have been well annotated. Then it would make sense to define "well annotated".

ADD REPLYlink written 3.9 years ago by dago2.5k
0
gravatar for h.mon
3.8 years ago by
h.mon24k
Brazil
h.mon24k wrote:

Read the introduction of this paper, and you will see the human genome is badly annotated. And if I remember right, 40% of the genes are still of unknown function! Really, an appaling job.

On a more serious tone, all genomes are still bad, because there is still a lot to be discovered. But some are worst than others, the "classic" model organisms - as human, mouse, fruit fly - have the better genomes (in sueqence coverage and annotation), all the others are worst, to a great extent because their annotation is almost completelly automatic, thus import errors from others annotations and introducing new errors.

ADD COMMENTlink written 3.8 years ago by h.mon24k
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