Question: Not Annotated Genome
gravatar for mariano.avino
4.6 years ago by
European Union
mariano.avino0 wrote:

Hi there,

Is there any 'model' organism (plant, animal, bacterial) out there you would say it has not been annotated or, at least, bad annotated?

Thank you very much in advance.




genome • 992 views
ADD COMMENTlink modified 4.5 years ago by h.mon28k • written 4.6 years ago by mariano.avino0

I guess most of the reference organisms with available genomes have been well annotated. Then it would make sense to define "well annotated".

ADD REPLYlink written 4.6 years ago by dago2.5k
gravatar for h.mon
4.5 years ago by
h.mon28k wrote:

Read the introduction of this paper, and you will see the human genome is badly annotated. And if I remember right, 40% of the genes are still of unknown function! Really, an appaling job.

On a more serious tone, all genomes are still bad, because there is still a lot to be discovered. But some are worst than others, the "classic" model organisms - as human, mouse, fruit fly - have the better genomes (in sueqence coverage and annotation), all the others are worst, to a great extent because their annotation is almost completelly automatic, thus import errors from others annotations and introducing new errors.

ADD COMMENTlink written 4.5 years ago by h.mon28k
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