Question: Calculate z-scores from GWAS summary stats

4

Nandini •

**880**wrote:Hello,

I need to calculate the z-scores from meta-GWAS summary stats. The association file has the following header

rs_id Allele1 Allele2 Freq1 Effect StdErr P.value

The 'effect' is the Beta coefficent. My understanding is

z-score=Effect/StdErr

Is that correct ? Also, are there any R packages that can do this ?

Many thanks