Question: Neep help understanding CYP genes nomenclature
gravatar for iwegbue
5.4 years ago by
United Kingdom, London
iwegbue0 wrote:

I read this statement about CYP genes on

Here is a Intermediate to extensive metabolizer: One copy of the CYP3A4*22 allele was detected. Therefore, this patient is expected to be an intermediate to extensive metabolizer. Reduced metabolism of drugs that are inactivated or activated by CYP3A4 is expected when compared to patients who are *1/*1. 

What does this mean? ...patients who are *1/*1...

cyp genetics • 1.0k views
ADD COMMENTlink modified 3.0 years ago by Biostar ♦♦ 20 • written 5.4 years ago by iwegbue0

Thank you so much for replying my question, Devon. I think I may have figured it out. 

*1/*1 refers to the 2 alleles of the SNP (in this case CYP3A4)

ADD REPLYlink written 5.4 years ago by iwegbue0
gravatar for Devon Ryan
5.4 years ago by
Devon Ryan96k
Freiburg, Germany
Devon Ryan96k wrote:

This isn't a bioinformatics question, but I'm not sure how easily you'll be able to find the answer via google. In short, the CYP family has its own specific nomenclature, with things like *22 being a specific genotype.

ADD COMMENTlink modified 5.4 years ago • written 5.4 years ago by Devon Ryan96k
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