Question: microarray data sets
0
gravatar for bioinfo
4.0 years ago by
bioinfo50
research
bioinfo50 wrote:


I collected 3 datasets with different platforms. My interest is to find out target genes using bioinformatics tools and some data mining approaches. But i am little bit confuse on how to validate my result without wet lab approaches..???

gene • 824 views
ADD COMMENTlink modified 4.0 years ago • written 4.0 years ago by bioinfo50

Thanks... If possible Can you please refer me some journal on that ????

ADD REPLYlink written 4.0 years ago by bioinfo50

Perhaps you can find a review article somewhere, this is more the sort of thing you'd find in a text book.
 

ADD REPLYlink written 4.0 years ago by Devon Ryan89k
0
gravatar for Devon Ryan
4.0 years ago by
Devon Ryan89k
Freiburg, Germany
Devon Ryan89k wrote:

Your options are:

  1. Find a dataset with known positive/negative results and run that through your prediction to see how close the results are.
  2. Do cross validation (or similar), though you might need more datasets.

Option 2 isn't really validation in the strictest sense, but it's as close as you can get without additional experiments.

ADD COMMENTlink written 4.0 years ago by Devon Ryan89k
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