Copy Number Variation (CNV) segmentation algorithm

Question

[gauravsingh.singh86]

Hi,

I am trying to understand how segmentation alogorithm exactly works for CNV's. I went through few papers but the information was too vague. I want to understand this algorithm end to end. Please help.

Answer 1

[Chris Miller]

I assume you mean "segmentation", and I'd start by reading the CBS paper:
http://www.ncbi.nlm.nih.gov/pubmed/15475419