carboxylesterases classification into subfamilies

Question

[xiaofeng.dong12]

Hi!

I want to classify the carboxylesterases genes into subfamilies. There are about 17 subfamilies for these gene, but it is varying a lots in different species. so it is hard to find reference species to plot a tree. Is there a good method other than a tree?

Many Thanks!

Answer 1

[cdsouthan]

The answer is no. Trees are the definitive way to visualise protein family relationships

Answer 2

[h.mon]

Even though protein families are defined in terms of evolutionary history, you may also classify them according to protein domains and / or sequence features.