I'm new on exome sequencing and bioinformatics analysis so I was wondering if someone could help me. I've generated a .VCF file from my exome data and now I need to see which variant is related to my disease (ocular disease). Are there any package that can perform such analysis? I'm using microsoft excel to make some initial filtering like phred score and segregation but don't know where to go from now on!!!!
Thanks and sorry for any mispeling!