I am a clinician, and have no particular expertise in genomics. I'm confused by much of what I see on dbSNP. Any help would be greatly appreciated! Thank you in advance.
What is the minor allele? What is the major allele? Is the major allele also known as the "wild type"?
According to NCBI, "The MAF is actually the second most frequent allele value”. http://www.ncbi.nlm.nih.gov/projects/SNP/docs/rs_attributes.html#gmaf
I'm not sure why reporting the second most frequent allele is helpful.
Can I use MAP/MinorAlleleCount to estimate prevalence of allele frequency?