Question: Are there any databases that collect datas about Synthetic Lethal gene pairs of human?
gravatar for Joe_daisy
4.5 years ago by
Joe_daisy20 wrote:

I want to search data about Synthetic Lethal gene pairs of human,are there any databases , Or some papers about that? Thanks very much...

synthetic lethal database • 1.8k views
ADD COMMENTlink modified 4.5 years ago by Giovanni M Dall'Olio26k • written 4.5 years ago by Joe_daisy20
gravatar for Giovanni M Dall'Olio
4.5 years ago by
London, UK
Giovanni M Dall'Olio26k wrote:

Check this paper by Jerbi-Alon 2014, where they developed DAISY, a method to predict synthetic lethal pairs:

They released a Cytoscape session file, containing all the synthetic lethal pairs synthetic dosage lethal pairs predicted.

In alternative you can contact the company Mission Therapeutics, which focuses on identifying new drug targets using synthetic lethality. I doubt they will release their data publicly, but depending on what you need you may propose them a collaboration or something like that.

ADD COMMENTlink written 4.5 years ago by Giovanni M Dall'Olio26k
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