Question: question about a term regarding copy number aberrations and genes involved in these areas.
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gravatar for mangfu100
3.8 years ago by
mangfu100700
Korea, Republic Of
mangfu100700 wrote:

Hi all.

In copy number analysis, as some of you already know, copy number variations consist of their segment size and amplitude level and genes involved in their regions. 

And also, it is obvious that CNVs that occurred in small segment size having few oncogenes might be considered as more important than other CNVs which are occurred in very long long regions having many oncogenes as well as other genes not previously implicated in cancer. 

From this point of view, the large size of arm-level CNVs makes it difficult to determine the specific target genes in contrast to focal CNVs which have great power to pinpoint the important genes targeted by these regions.

And my problem is how to express those concept to deliver the compressed notion to other people in a easy way?

Is there any frequently used terms indicating the density of genes in copy number segments? 

sequencing next-gen genome • 990 views
ADD COMMENTlink written 3.8 years ago by mangfu100700
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