I think it might be a very silly question, therefore sorry about my ignorance.
Imagine a RNA-seq data set with n samples, and I want to determine the correlation between each other.
After count normalization, we can perform a correlation between each sample, using Pearson, Spearman, or other one. In a gene to gene correlation I do can understand how these tests works.
But if I have a huge data set (n samples) with m genes, how the correlation test works? Can anybody answer me please?