Off topic:What Substitution Matrices Are Available For Blast?
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12.4 years ago
Ryan Thompson ★ 3.6k

I'm having trouble locating documentation on what substitution matrices are supported by command-line BLAST+ tools. Do they have a specific set of matrices built in? Are they hidden in a directory somewhere? Can I add my preferred one if it is not supported by default?

In particular, I'd like to use the BLOSUM100 matrix, because I want higher mismatch penalties.

blast • 5.2k views
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