De novo mutation rate per base pair

Question

[897598644]

Excuse me:

Could you please tell me what is the formula ot de novo mutation rate per base pair?

Many thanks in advance!

[lh3]

~1.2e-8 per generation.

[897598644]

So what is the formula? I want to calculate the result of my data.

Thanks.

Answer 1

[h.mon]

This blog post links to several interesting papers, you can probably follow their protocols. The ~1.2e-8 figure is from this paper, also linked on the blog post.

[897598644]

So how did you think if it was less than 1.2e-8. Was it normal? How did you understand the question?