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8.7 years ago
Shicheng Guo
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9.4k
Hi my colleagues,
Is there anyone can share a R code for variable methylation region identification.
Best regards,
VMR: http://epigenie.com/variable-methylation-regions-and-missing-heritability-with-dr-andrew-feinberg/
VMR: Nat Genet. 2009 Feb;41(2):178-86. doi: 10.1038/ng.298. Epub 2009 Jan 18
VMR: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729128/
champ.mvp: http://bioconductor.org/packages/devel/bioc/html/ChAMP.html
Significance: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276267/
You know, the formula or the code would be great helpful for the follower or the users.
Are you looking for DMRs (Differentially methylated Regions)? or are variable methylation regions something different?
7 weeks later, but they're different. VMRs just show higher variation. These could be important for things like epigenetic inheritance.