Question: Question about mutation spectrum
0
gravatar for mangfu100
4.6 years ago by
mangfu100730
Korea, Republic Of
mangfu100730 wrote:

Hi all.

I am wondering how to calculate the mutation spectrum.

In paper, I found notations below which seem to refer the mutation spectrum.

C:G-> G:C

C:G -> T:A

C:G -> A:T (I skipped the all of the notations due to space)

My questions is as below.

1. How to interpret notation above? what is meaning of colon? (for dividing?)

why the C,G and G,C (C:G -> G:C) is paired ? is it convention?

Finally How to calculate C/G->T/A? 

I am looking forward to your kindly answer :)

sequencing next-gen genome • 1.4k views
ADD COMMENTlink modified 4.6 years ago by Chirag Nepal2.2k • written 4.6 years ago by mangfu100730
0
gravatar for Chirag Nepal
4.6 years ago by
Chirag Nepal2.2k
Copenhagen
Chirag Nepal2.2k wrote:

The convention of reading is:

C:G > T:A means C is mutated to T and G is mutated to A, and so on for others.

ADD COMMENTlink written 4.6 years ago by Chirag Nepal2.2k

Thanks for your reply.

To better understand, let me give an example.

the number of C->T mutations is 5 and the number of G->A mutations is 11.

than C:G->T:A is 16. Is that right?

ADD REPLYlink written 4.6 years ago by mangfu100730
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