I'm working on reconstruction and analysis of a co-expression network of a siganl pathway in breast tumor. I have GEO data just for 10 patients with breast tumors with specified features. Are these number of sample suitable for network analysis? Is this network acceptable?
On the other hand I want to reconstruct a co-expression network for differentiation of ESCs to neural cells. GEO data is limited for this study. forexample I have a dataset which contains expression profile of 4 days of differentiation , each contains 3 replicates. Is it a good dataset for my analysis for reconstruction of network.??