Classification of Repetitive DNA with more details
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8.6 years ago
M K ▴ 660

I am looking for source that classify the repetitive DNA in details, I mean classification according to the repetitiveness, size , location, importance, because I am going to use it as reference. I found some sources talk about the repetitiveness and they classify them to highly repetitive and moderately repetitive and they put satellite DNA as an example of highly repetitive and put micorsatellite and mini satellite under tandem repeats in the moderately repetitive so I got confused.

genome sequencing • 2.7k views
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There are plenty of tools for characterizing genomic repeats depending on what type of data you have and what your goals are. I noticed you included the rna-seq tag, is this the type of data you want to search for repeats? This is not ideal for what you listed but there are some things you can do.

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I am not looking for any tools. I am looking for the theoretical classification.

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Ah, that wasn't clear to me. I can answer these questions because this is my field of study, but biostars is for bioinformatics questions, not this type of general biology questions. I recommend you do some searching in this case because wikipedia has descriptions of all of these terms. If you have a specific evolutionary or functional question, that would be a good thing to ask on biology stackexchange (or here, if it relates to informatics).

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It is not entirely clear what you are asking for.

  1. What kind of repeats? Short tandem repeats, SINEs, LINEs etc?
  2. On what genome?
  3. Define "repetitiveness" and "importance"?

Repeats have been classified in Repbase. http://www.girinst.org/repbase/

Reference genomes have a RepeatMasker track which can be used. Sizes and locations will be estimates due to problems with assembly of repetitive elements. Sizes of tandem repeats (aka VNTR, Variable Number Tandem Repeats) are known to be highly variable between individuals.

In short, repeats are poorly annotated and poorly understood. I don't think the database you are describing, currently exists.

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